Job Description
Job Summary: Zymo Research is looking for a dynamic individual to join our Chemistry Team! We are seeking a highly skilled Organic Chemist or Biochemist with a strong foundation in chemistry and hands-on experience in bioconjugation, reagent formulation, synthesis, and analytical characterization. This role will focus on surface modification and functionalization of magnetic beads for applications in molecular biology, diagnostics, and life science research. The ideal candidate will have deep knowledge of reaction chemistry, biomolecule interactions, and experience developing robust and scalable conjugation and production workflows.
Join us in making a meaningful impact!
Essential Duties and Responsibilities: 1. Magnetic Bead Surface Chemistry & Conjugation
- Develop, optimize, and scale surface modifications of various magnetic bead platforms.
- Perform covalent and affinity-based conjugation of biomolecules, including proteins, antibodies, nucleic acids, linkers and other ligands.
- Evaluate and optimize ligand density, coupling efficiency, stability, and functional performance.
2. Reagent Formulation & Synthesis
- Formulate buffer systems, blocking reagents, activation chemistries, and stabilization solutions.
- Design and perform organic syntheses for linkers, crosslinkers, activated molecules, and surface-reactive intermediates.
- Develop and validate reproducible reagent preparations suitable for scale-up and manufacturing.
3. Documentation
- Produce documentation and data needed for product launch and marketing.
- Develop and write SOPs, batch records, experiment records and development reports.
- Responsible in tech transfer to manufacturing and assist in troubleshooting production issues.
4. Communication
- Communicate effectively with interdisciplinary teams.
- Meeting regularly with the research team to discuss project progress.
- Present findings internally and externally and contribute to research publications.
Required Qualifications: - Ph.D. or M.S. in Organic Chemistry, Biochemistry, Chemical Biology, or related discipline.
- Strong expertise in bioconjugation chemistry (e.g., amine, thiol, click chemistry, EDC/NHS).
- Hands-on experience in surface functionalization and modification of nanoparticles, resins, or magnetic beads.
- Proficiency in analytical chemistry and characterization techniques.
- Demonstrated ability to design, plan, and execute complex chemistry workflows independently.
Preferred Qualifications: - Experience with bead-based assays (e.g., immunoprecipitation, nucleic acid purification, immunoassays).
- Familiarity with design for manufacturability, scale-up, and reagent stabilization.
About Us: Since its inception in 1994, Zymo Research has been proudly serving the scientific community by providing innovative, reliable, and high-quality research tools and products. Whether it's DNA, RNA, epigenetics, microbiomics, protein, or yeast-based research, our philosophy remains the same: To provide the highest quality products in the industry while ensuring they are both simple to use and reliable in their performance.
Recognized as a Top Workplace by the Orange County Register in 2021, 2022, and named a Top Workplace USA in 2023, Zymo Research continues to be a vibrant community where employees thrive, feel connected, and are inspired by their work. If you are passionate about contributing to scientific advancement and want to be part of an exceptional team in a dynamic, growing company, we'd love to hear from you!
Compensation, Benefits, and Perks: The estimated base compensation range for this position is $70,000 - $110,000 a year at the time of posting. Actual compensation details will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors.
Zymo Research also offers competitive benefits and perks including:
- Medical, Dental, Vision, and Life Insurance Coverages
- EAP Sessions
- Vacation Time plus Company Holidays
- Paid Sick Leave
- Generous 401(K) with matching
- Employee Referral Bonus
- Complimentary fruit, snacks, and beverages
- Complimentary catered lunches on Thursdays
- Complimentary EV Charging
Equal Employment Opportunity Employer: Zymo Research welcomes candidates of all backgrounds. These include sex, age, color, race, religion, marital status, national origin, ancestry, sexual orientation, gender, gender identity, gender expression, physical & mental disability, medical condition, genetic information, military and veteran status, or any other protected status as defined by federal, state, or local law.
Location: Onsite - Zymo Research Operations - 2961 Dow Ave., Tustin, CA 92780
Disclaimer: At Zymo, we take the integrity of our hiring process seriously. Please be aware of fraudulent recruitment activities that may use our name to deceive job seekers. We will never ask for payment, sensitive personal information, or financial details during the recruitment process.
All legitimate communications will come from an official Zymo or TriNet Hiring email address. If you are contacted by anyone claiming to represent us using a free email service (e.g., Gmail, Yahoo, Hotmail) or asking for payment, please treat this as fraudulent and report it immediately to
[email protected]
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